Dr. Yan Gao Canada FAM72A potentiates APOBEC3B-driven cytidine deamination and mutagenic repair to promote colorectal tumorigenesis Yan Gao 1, Mohammad Khakpoor Koosheh1, Bhupesh Thakur 1, Maribel Berru1, Alberto Martin 1 1 Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada Abstract Background APOBEC3B (A3B) promotes cytidine-to-uracil (C‚ÜíU) deamination and generates clustered mutations characteristic [...]

Emmanuel Amewu Sghana The association between submicroscopic Plasmodium infections and gut microbiota among children in Ahanta West, Ghana Emmanuel K. A. Amewu1, Rosemond Enam Mawuenyega2, Bismark Koduah2, Alexander Kwarteng2,3, Amma A. Larbi2 1. Department of Molecular Medicine, School of Medical Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana 2. Department of Biochemistry [...]

Christos Tsagkaris Switzerland Safeguarding cancer care during crises: Lessons from the Institute of Cancer and Crisis Christos Tsagkaris1, Jemma Arakelyan2 Abstract Background Crises challenge health systems and highlight the essential role of civil society in maintaining care beyond formal structures. While emergency responses often prioritise trauma, infectious disease, and acute care, the convergence of [...]

Emily Siniscalco U.S.A. Mucosal immunization induces linked local and systemic humoral responses Emily R. Siniscalco1,2; Hailong Meng3; Gisela Gabernet3; Gaspar. A. Pacheco4,5,6,7; Shahab Saghaei4,5,6,7; Sydney I. Ramirez8,9; L. Benjamin Hills9,10; Farhoud Faraji9,11; Shuting Chen1; Xiangyun Yin1,12; Christine Dien1,3,13,19; Laura R. Hoyt1; Elise G. Liu13; Abel Barrett14; Neima Briggs15; Adam Williams2,16; Vipul Shukla2,17; Shane Crotty8,9, Duane [...]

Javier Orozco-Cordoba Mexico Trim33 regulates TH9 differentiation and in vivo function. Javier Orozco-Cordoba1, Eugenio Contreras-Castillo1, Ofelia Muñoz-Paleta1, Daniel Zambrano-Romero1, Jose Luis Ramos-Balderas1, Paula Licona-Limon1 1. Instituto de Fisiologia Celular, UNAM. Abstract Background The TGF-β signaling pathway has been extensively studied in CD4+ T cells, particularly in TH17, Treg, and, more recently in TH9 cells, characterized [...]

Débora Silva Pinto Brazil Characterization of Saint Louis encephalitis virus (SLEV) neuroinfection in central nervous system (CNS) human cell models and IFNAR -/- mice. D√©bora Silva Pinto1; D√©borah Pereira Pina da Silva1,2; Luan Rocha Lima1; Sharton Vin√≠cius Antunes Coelho1; Luciana Barros de Arruda1. 1. Universidade Federal do Rio de Janeiro- UFRJ; 2. Universidade Federal do [...]

Dr. Aranzazu Arias-Rojas U.S.A. Infection-induced elevation of gut glycosaminoglycans fosters microbiota expansion in Drosophila melanogaster Aranzazu Arias-Rojas1,4, Marko Rubinić 1,2 , Jasmin Albiez1,5,6, Dagmar Frahm1, Robert Hurwitz3, Igor Iatsenko1,* 1 Research group Genetics of host-microbe interactions, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany 2 Humboldt-Universität zu Berlin, Faculty of Life Sciences, [...]

Dr. Jongwon Lim U.S.A. A biphasic dried blood matrix platform for rapid, extraction-free detection of DNA and RNA pathogens from whole blood Jongwon Lim1,2,3, Hankeun Lee2,4, Matthew Wester1,2, Katherine Koprowski1,2, An Bao Van1,2,5, Enrique Valera1,2,6, Brian T Cunningham1,2,4,6,7,8,9, Rashid Bashir1,2,4,6,10,11,12,13 1 Department of Bioengineering, Grainger College of Engineering, University of Illinois at Urbana–Champaign, Urbana, IL [...]

Asad Channa Pakistan AI-assisted MRI-based classification of brain tumors for improved clinical diagnosis Asad Channa¬π ¬π Department of Computer Science, Quaid-e-Awam University of Engineering, Science & Technology (QUEST), Nawabshah, Pakistan Abstract Background Detecting brain tumors early is crucial for ensuring effective treatment and better outcomes for patients. However, diagnosing tumors from MRI scans can be [...]

Claudia Sahd Brazil Climate-driven dengue forecasting: SARIMA/SARIMAX models and web application Claudia Stoeglehner Sahd1, Alison Henrique Marcelino1, Elisângela Aparecida da Silva Lizzi1 Mathematics Department, Graduate Program in Bioinformatics, University Tecnology Federal of Paraná - (UTFPR), Paraná, Brazil Abstract Background Climate change has intensified arboviral transmission by altering temperature, humidity, and precipitation patterns that favor [...]