Adriana Musteata and Victoria Musteata Moldova Global wellbeing and health in the current world Adriana Musteata1, Victoria Musteata1 1. High School "Vasile Vasilache", Chisinau, Republic of Moldova Abstract Background Wellbeing (WB) is the absence of diseases, as well as a complex combination of a person's physical, mental, emotional and social health factors. The actual [...]

Asmaa Galal Egypt Enhanced bone regeneration using mesenchymal stem cell-loaded 3D-printed alginate-calcium titanate scaffolds: A calvarial defect model study Neveen A. Salem a, Shaimaa A. ElShebiney a, Mostafa Mabrouk b, Mohamed S. Kishta c d, Asmaa F. Galal a, Lamyaa Osama b, Hanan H. Beherei b a Narcotics, Ergogenics, and Poisons Department, Medical Research and [...]

Sabrina Dhooge Argentina Peripheral and tumor immune signatures predict response to immunotherapy in advanced HER2-negative breast cancer Sabrina Dhooge¹, Ekaterina Friebel², Boffelli Lucia¹, Dutto Jeremias¹, Flores Ana Paula¹, Bustos Jeremias¹, Biasi Pilar ¹, Silvana Mouron³, Miguel Quintela-Fandino³, Burkhard Becher² Mariana Maccioni¹ and Nicolas Nuñez ¹ ¹Centro de Investigaciones en Bioquímica Clínica e Inmunología, CIBICI-CONICET, Departamento [...]

Mohadeseh Ahmadvand Canada MATH-only proteins (MOPs): Emerging immunoregulators in inflammation-related diseases Mohadeseh Ahmadvand1,2, Azin Tariniya Gilani1, Haroon Nigil2, Ali Abdul-Sater1* 1.School of Kinesiology and Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada 2.Schroeder Arthritis Institute, Toronto Western Hospital, Spondylitis Program, University Health Network, Toronto, ON, Canada Abstract Background Inflammation is a vital [...]

Dr. Anastasia Nijnik Canada Loss of MYSM1 deubiquitinase catalytic activity protects against MYC-driven lymphoma Dania Shaban 1,2,#, Viktoria Plackoska 1,2,#, Yue Liang 1,2, Nay Najm 1,2, Francis Robert 3,4, Sidong Huang 3,4,5, Anastasia Nijnik 1,2* 1 Department of Physiology, McGill University, Montreal, QC, Canada 2 McGill University Research Centre on Complex Traits, McGill University, QC, [...]

Felipe Pinto Brazil Deletion of natterin impairs NLRP3 inflammasome activation and host defense against Salmonella typhimurium in zebrafish Felipe Justiniano Pinto1; Darlan Gusso1; Jefferson Thiago Gonçalves Bernardo1; Aline Ingrid Andrade-Barros1; Carlos DeOcesano-Pereira2; Monica Lopes-Ferreira1; Carla Lima1 1. Plataforma Zebrafish of the Laboratory of Applied Toxinology (CeTICs/FAPESP), Instituto Butantan, São Paulo, Brasil 2. Centre of Excellence [...]

Dr. Fernando Flores-Guzman U.S.A. Bone marrow dormant tumor cells maintain reactive memory CD8 T cells Flores-Guzman Fernando1,5, Federico-Guerrero Alfonso2, Morales-Ramirez Claudia A3, Carrasco-Ramirez Liliana4, Umansky Viktor5, Carrasco-Ramirez Elba6 1. Surgery Department, University of Colorado, Denver Colorado, USA 2. Microbiology Department, School of Medicine, UNAM, Mexico City 3. General Hospital Dr. Enrique Cabrera, Mexico City 4. [...]

Dr. Valentina Venzin France CD4+ T cells license Kupffer cells to produce IL-27 and reverse CD8+ T cell dysfunction induced by hepatocellular priming Valentina Venzin1,2, Cristian G. Beccaria1,2, Chiara Perucchini1,2, Pietro Delfino1, Elisa B. Bono1, Leonardo Giustini1, Federica Moalli1,3, Marta Grillo1,2, Valeria Fumagalli1,2, Chiara Laura1,2,4, Pietro Di Lucia1,2, Katharina Reinhard5, Jutta Petschenka6, Tana Annmarie Omokoko5, [...]

Dr. Yan Gao Canada FAM72A potentiates APOBEC3B-driven cytidine deamination and mutagenic repair to promote colorectal tumorigenesis Yan Gao 1, Mohammad Khakpoor Koosheh1, Bhupesh Thakur 1, Maribel Berru1, Alberto Martin 1 1 Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada Abstract Background APOBEC3B (A3B) promotes cytidine-to-uracil (C‚ÜíU) deamination and generates clustered mutations characteristic [...]