Nermin M. Mohamed Egypt Uncovering the Multifaceted Role of the Kinetochore Scaffold 1 in Hepatocellular Carcinoma: In-Silico Analysis and CRISPR-Cas9 Experimental Study Nermin M. Mohamed1, Rania Hassan Mohamed2, Mahmoud M. Elhefnawi3, Nadia M. Hamdy1 1 Biochemistry Department, Faculty of Pharmacy, Ain Shams University, Abassia 11566, Cairo, Egypt, 2 Biochemistry Department, Faculty of Science, Ain [...]

Emmanuel Fajemisin South Africa Antibody Bioconjugates as targeted therapeutics for CD64+ dysfunctional monocytes/macrophages implicated in cancer types. Emmanuel Adebowale Fajemisin 1, Olusiji Alex Akinrinmade 1, 2 , Stefan Barth 1,3. 1 Medical Biotechnology and Immunotherapy Research Unit, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, Universityof Cape Town, Cape Town 7700, [...]

Haritha Manoj United States TCR-Mediated Bacterial Recognition in Colorectal Cancer: Testing TH17-Associated TCRs for Antigen Specificity Haritha Manoj1,2, Pakhi Birla1,2, Wanting Shan1,2, Ying Zheng1,2, Hongni Fan1,2, Hadley Beauregard5, Kellie N. Smith1,2, Drew M. Pardoll1,2, Fyza Shaikh1,2, Cynthia L. Sears2,5, Franck Housseau1,2,6 1 Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA 2 [...]

Taras Zadvornyi Ukraine Association of Collagen Maturity with the Clinicopathological Characteristics of Prostate Cancer Zadvornyi T., Mushii O., Pavlova A., Burda T., Shevchuk A., Lukianova N. R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of the National Academy of Sciences of Ukraine, Kyiv, Ukraine Abstract Background It has been demonstrated that extracellular matrix [...]

Mustak Ahamed India Evaluation of Antibiotic Prescribing Patterns in Surgical Prophylaxis at a Public Sector Hospital Mustak Ahamed¹*, Garry Hunjan¹, Dr. Khadga Raj Aran¹ 1Department of Pharmacy Practice, ISF College of Pharmacy (An Autonomous College), Moga-142001, Punjab, India. Abstract Background Surgical site infections (SSIs) play a major role in postoperative morbidity, hospitalization, and excessive [...]

Manahil Imran Pakistan Exploring Soil Streptomyces as a Source of Antimicrobial Metabolites Against Multidrug-Resistant Pathogens Manahil Imran1, Saba Kiran1, Saman Taj1, Waqar Rauf1, Mazhar Iqbal1 1. Health Biotechnology Division. National Institute for Biotechnology and Genetics Engineering, Pakistan Institute of Engineering & Applied Sciences (NIBGE-C, PIEAS), Jhang Road, Faisalabad, Pakistan. Abstract Background Multidrug-resistant (MDR) pathogens have [...]

Saba Farooq Farooq Pakistan Pathogenic SNP Network Enhancing IL-2/JAK-STAT Signaling and T-cell Responses in Celiac Disease Saba Farooq1 and Syeda Marriam Bakhtiar1* 1. Genetic and Epidemiology Research Group, Department of Bioinformatics and Biosciences, Capital University of Science and Technology, Islamabad, Pakistan. Abstract Background Celiac disease is an immune-mediated enteropathy characterized by aberrant T-cell activation in [...]

Rania Mohamed Egypt The diabetic type 2 microenvironment deteriorates the gamma delta T cell function Rania Hassan Mohamed1, Ali E. Elhargy2, Shireen Magdy2, Abd ElRahman Abouzid2, Nagwa ElBadry2 1. Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, Egypt 2. Center of Excellence for Stem Cells and Regenerative Medicine, Zewail City of Science and [...]

Soumya Majumdar India Targeting spinal glutamatergic pain pathways using Rutin. Soumya Majumdar1, Sabnur Parvage1, Tuhin Bhattacharya1, Sanjit Dey1,2,3* 1. Department of Physiology, University of Calcutta, 92 APC Road, Kolkata 70009, West Bengal, India. 2. Centre for Nanoscience and Nanotechnology (CRNN), University of Calcutta. 3. Centre with Potential for Excellence in Particular Area (CPEPA), University of [...]

Vaishnavi T India Somatic PTEN Alterations in an Indian Endometrial Cancer Cohort: Prevalence and Therapeutic Implications. Vaishnavi.T1, Dr Tina Bhardwaj1 1.Department of Oncogenomics, Lifecell Diagnostics, No. 26, Vandalur-Kelambakkam Main Road, Keelakottaiyur, Chennai, Tamil Nadu, India. Abstract Background Endometrial carcinoma (EC) is one of the most common gynecological malignancies globally. The tumor suppressor gene PTEN is [...]