Liudmila Benni Moldova DMARD treatment of rheumatoid arthritis Liudmila Benni, Elena Deseatnicova Abstract Background Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation, progressive structural damage, and systemic complications. Disease-modifying anti-rheumatic drugs (DMARDs) form the cornerstone of RA treatment, aiming to control disease activity and prevent long-term joint damage. Conventional synthetic [...]

Valeriia Kolotusha Ukraine Approach to P16 and Ki-67 in the Cervical Intraepithelial Neoplasia staging Valeriia Kolotusha1, Viktoriia Khoperiia1 1. Taras Schevchenko National University of Kyiv Abstract Background Cervical cancer is the second most common malignancy in women, which originates from cervical intraepithelial neoplasia (CIN). Accurate screening and diagnosing are increasingly in demand for early [...]

Olabina Viktoriia Moldiva Features of Osteoporosis in Perimenopausal Women and Bone Tissue Condition the Perimenopausal Period Olabina Viktoriia, Deseatnicova Elena Abstract Background Osteoporosis is a systemic skeletal disorder characterized by decreased bone mass and structural deterioration, leading to an increased risk of fractures. Perimenopausal women are at a particularly high risk due to hormonal [...]

João Antonio Ribeiro De Sousa Brazil The role of the bone marrow microenvironment in leukemia progression and therapeutic resistance 1. João Antonio Ribeiro de Sousa, UNINASSAU College, Petrolina, Brazil. Abstract Background Leukemia is a type of hematologic cancer characterized by the abnormal proliferation of bone marrow progenitor cells. In recent years, the role of [...]

Samah Kotb Nasr Eldeen Egypt Knockdown of CD-74 in the Proliferative and Apoptotic Activity of Breast Cancer Cells Hussain Al Ssadh1, Waleed Al Abdulmonem2*, Zafar Rasheed3, Inamul Hasan Madar4, Jamila Alhoderi1, Samah K. Nasr Eldeen 5,6, Ali Alradhwan7, Noura Alasmael8, Abdullah Alkhamiss2, Nelson Fernández1 1School of Biological Sciences, University of Essex, Colchester, UK; 2Department [...]

Sara Gharib Canada Determination of the Neurobiological Origins of the CHD8 Phenotype Using Genetic Cre Drivers Sara Gharib¹, Ritah Sansa², Esther M. Garfield², Samantha Dhanani², Ariine Hoque², Muhammad O. Chohan², Jeremy Veenstra-VanderWeele², Rebecca Muhle² 1. Department of Neuroscience and Behavior, Barnard College, Columbia University, New York, NY, USA 2. Department of Adolescent Psychiatry, New [...]