2025848

Stefan Mereiter Austria Tumor sialylation controls effective anti-cancer immunity in breast cancer Stefan Mereiter1,2, Gustav Jonsson1,2, Tiago Oliveira1,2, Josef M. Penninger1,2,3,4 1. Eric Kandel Institute, Department of Laboratory Medicine, Medical University of Vienna, Spitalgasse 23, Vienna, Austria 2. Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Dr. Bohr-Gasse [...]

2025392

Taras V. Zadvornyi Ukraine EXPRESSION OF COLLAGEN DENSITY-REGULATORY FACTORS IN PROSTATE CANCER Zadvornyi T., Mushii O., Pavlova A., Burda T., Shevchuk A., Kashuba E., Lukianova N. R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of the National Academy of Sciences of Ukraine, Kyiv, Ukraine Abstract Background The growth of malignant neoplasms, including prostate [...]

2025445

Arnold Abakah Ghana Conformational Dynamics and Active Site Flexibility in the Pseudomonas aeruginosa LasR Protein: Inhibiting the Quorum Sensing Receptor Prince Manu1,3, Arnold Abakah2, Paa Kwesi Anfu2, Priscilla Osei-Poku2,3, Alexander Kwarteng2,3* 1. Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana 2. Department of Biochemistry and Biotechnology, Kwame Nkrumah University of [...]

2025312

Taiwo O. Ojo Nigeria Repurposing FDA-Approved Cardiovascular Drugs to Inhibit RAGE in Alzheimer’s Disease through Virtual Screening and Molecular Dynamics Investigation Taiwo Ooreoluwa Ojo1*, Temitope Isaac Adelusi1,2, Olawale Quadri Bolaji1,3, Benedicta Quainoo4, Jonathan Cudjoe5, Michael Olanrewaju Faloyo6, Omotoyosi Olanrewaju Osalaye6, Oluwabamise Emmanuel Elegbeleye1, Ibrahim Damilare Boyenle7, Abdul-Quddus Kehinde Oyedele8, Mojeed Ayoola Ashiru4, Abdeen Tunde [...]

2025267

Laura Nicolucci Canada Investigating the Effects on Targeting the TRAF1/PKN-1 Signalling Axis in Inflammation Laura Nicolucci1, Ali. Abdul-Sater1 1. Department if Kinesiology and Health Science, York University, Toronto, Canada Abstract Background Tumor necrosis factor receptor-associated factor 1 (TRAF1) is a signaling adaptor protein in lymphocytes and monocytes. In monocytes, TRAF1 attenuates inflammatory signaling by [...]

2025217

Prabaran R United States Deciphering enzymatic potential in metagenomic reads through DNA language model R Prabakaran1,2, Yana Bromberg1,2 1. Department of Biology, Emory University, Atlanta, GA 2. Department of Computer Science, Emory University, Atlanta, GA Abstract Background The microbial world, home to an extensive array of bacterial species, plays a fundamental role in shaping Earth's [...]

2025395

Ludmila Sidorenko Moldova New biotechnology in biosignal analysis of cardiorhythmograms to visualize triggers for predicting atrial fibrillation onset Ludmila Sidorenko1, Anand Muraleedharan1, Daria Zalesskaia1, Anaswara Vijayakumar1, Fauizi Mohammad1, Vitalie Cobzac2, Viorel Nacu2, Niels Wessel3,4 1. Department of Molecular Biology and Human Genetics, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Republic of Moldova 2. [...]

2025790

Gillian Mbambo United States Host immunotranscriptomics during malaria infection and malaria-schistosomiasis co-infection in a Malian pediatric cohort Gillian Mbambo1, Joana C. Silva1, Kirsten E Lyke2, Abdoulaye Dabo3, Charles Arama3, Issa Diarra3, Ogobara K Doumbo3 1. Institute of Genome Sciences, University of Maryland, School of Medicine, Baltimore, Maryland 2. Center for Vaccine Development and Global Health, [...]

2025444

Raunak Kar India Understanding the biology of CD4 cytotoxic T lymphocytes (CD4-CTLs) in humans Raunak Kar1, Shreya Sinha1, Anjali Sharma2, Veena S. Patil1 1. National Institute of Immunology, New Delhi, India 2. VMMC and Safdarjung Hospital, New Delhi Abstract Background The acquisition of immunological memory to infection is a hallmark of protective immunity. Naïve T-cells [...]

2025297

Fernando G. I. Freire Brazil Inborn Errors in the Type I Interferon Signaling Pathway in Children with Multisystem Inflammatory Syndrome Associated with SARS-CoV-2 Infection Fernando Freire1,2, Raquel Bispo1,3, Ryan Francisco1, Sâmek Novaes1, Pablo Oliveira1 1. Laboratory of Genomics and Complex Diseases, University Federal da Bahia, Brazil 2. Laboratory of Immunology and Molecular Biology, University [...]

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