Natalia Ogrodnik Canada Discovering small molecule inhibitors of a novel dual-specificity phosphatase to treat inflammatory bowel disease Natalia Ogrodnik1, Saurav Roy Choudhury1, Eva Warwick1, Daniel Mao2, Zemin Zhang2, Jason Yang1, Frank Sicheri2,3,4, Alberto Martin1 1. Department of Immunology, University of Toronto, Toronto, ON, Canada 2. Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada [...]
Aneta Ostróżka-Cieślik Poland Investigation of thermosensitive insulin hydrogels in the context of supporting chronic wound treatment Aneta Ostróżka-Cieślik, Marcin Przybyła, Barbara Dolińska Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Jedności Street 8b, 41-208 Sosnowiec, Poland Abstract Background BACKGROUND: Recent preclinical and clinical studies indicate the high efficacy of [...]
Rui Farinha Portugal Scaling up of a nanoformulation loaded with bioactive compounds for skin aging prevention Rui P. Farinha1, Joana A. Loureiro2, 3, 4 1 R&D, BNanoTech, Porto, Portugal 2 Department of Mechanical Engineering, Faculty of Engineering, University of Porto, Porto, Portugal 3 LEPABE - Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty [...]
Nada El-Sayed Egypt Mangiferin mitigates methotrexate-induced liver injury and suppresses hepatic stellate cells activation: imperative role of Nrf2/NF-κB/NLRP3 axis Nada M. El-Sayed1,2, Esther T. Menze1, Mariane G. Tadros1, Diana M.F. Hanna1 1. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, 11566 Cairo, Egypt. 2. School of Life and Medical Sciences, University of [...]
Mahdi Yousefian Iran Harnessing Base editing with CRISPR-Cas13 and machine learning for precision gene therapy in rare genetic disorder Mahdi Yousefian1, Maryam Baharmast2 1Islamic Azad University of Tehran Medical Science , www.Orcid.org/0009-0006-7619-523X, www.Linkedin.com/in/mahdiyousefian ,Yousefian.Mahdi2004@gmail.com 2Islamic Azad University of Tehran Medical Science , www.Orcid.org/0009-0001-0839-9779,, www.Linkedin.com/in/maryam-baharmast Abstract Background Sickle cell disease (SCD) is a genetic disorder caused [...]
Roumaissaa Belkacem Algeria First report of enterocin genes in autochthonous Lacticaseibacillus paracasei and Levilactobacillus brevis strains Roumaissaa Belkacem1, Qada Benameur2, Smaranda Cr˘ aciun3, George Cosmin Nad˘as3, Adriana Gy¨ orke 4, Hajer Kilani5. 1.Laboratory of Sciences and Techniques of Animal Production, Faculty of Nature and Life Sciences, University Abdelhamid Ibn Badis of Mostaganem, 27000, Mostaganem, Algeria [...]
Samuel Appiagyei Ghana The incidence of surgical site infections after emergency abdominal surgeries; a longitudinal study at Korle Bu Teaching Hospital, Surgical Departmen Samuel Appiagyei1,2, Antoinette Bediako-Bowan1,3, Gloria Asare1, Felicia Amezugbe1 1. University of Ghana Medical School, Accra, Ghana 2. Urology and Nephrology Center of Excellence, Korle Bu Teaching Hospital, Accra, Ghana 3. Surgical Department, [...]
Sachidananda Behera India An SNF-Integrated Hybrid Convolutional Neural Network for Drug–Drug Interaction Prediction in Cancer Patients Sachidananda Behera1,2; Deepa Kumari3; Subhrakanta Panda3; Parool Gupta2,4; Jitendra Kumar Singh2 1. Department of Pharmacy, AISECT University, Hazaribagh, Jharkhand, India. 2. Department of Research and Clinical Trials, S. S. Hospital and Research Institute, Patna, India 3. CSIS Department, BITS-Pilani, [...]
Fami Israyusnita Indonesia COMPARISON OF PICHIA PASTORIS AND HANSENULA POLYMORPHA AS L1 PROTEIN HPV45 VIRUS LIKE PARTICLE EXPRESSION PLATFORM Fami Israyusnita1,2, Astrid Shabrina Kusumareswari3, Astutiati Nurhasanah1*, Nihayatul Karimah1 1. Centre for Vaccine and Drugs Research, National Research and Innovation Agency (BRIN), Banten 15314, Indonesia 2. Master Program of Biomedical Science, Faculty of Medicine, Universitas Indonesia, [...]
Manal Ahmed Egypt CAR-Engineered Natural Killer Cells: Shaping the Future of Cancer Immunotherapy Manal M E Ahmed Pharmacology Department, Medical Research and Clinical Studies Institute, National Research Centre, Giza, Egypt Abstract Background Chimeric antigen receptor (CAR) technology has revolutionized cancer therapy, and natural killer (NK) cells are rapidly emerging as the next-generation platform in this [...]