Dr. Yan Gao Canada FAM72A potentiates APOBEC3B-driven cytidine deamination and mutagenic repair to promote colorectal tumorigenesis Yan Gao 1, Mohammad Khakpoor Koosheh1, Bhupesh Thakur 1, Maribel Berru1, Alberto Martin 1 1 Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada Abstract Background APOBEC3B (A3B) promotes cytidine-to-uracil (C‚ÜíU) deamination and generates clustered mutations characteristic [...]
Bright Afranie United States Role of hypoxia in coronary angiogenesis: Hypoxia stimulate SOX17-mediated- but repress APJ-mediated-Coronary Angiogenesis in developing mouse heart Bright O. Afranie, Chhiring Sherpa, Bryce Kushal, Alyx Panoncillo, Ken Reed, Felix Addo, Rupak Parajuli, and Bikram Sharma, PhD. 1.Department of Biology, Ball State University, Muncie, IN, USA Abstract Background Coronary Artery Disease [...]
María Moya Navamuel Panama Natural products as enhancers of tumor antigen presentation and immune sensitivity in colorectal cancer models María Moya-Navamuel1,3, Olga Genilloud2 and Timothy M Thomson1,4 1. Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT-AIP), Panama City, Panama2. Fundación MEDINA, Granada, Spain 3. Doctoral Program, Department of Biotechnology, Universitat Politècnica de València [...]
Nermin M. Mohamed Egypt Uncovering the Multifaceted Role of the Kinetochore Scaffold 1 in Hepatocellular Carcinoma: In-Silico Analysis and CRISPR-Cas9 Experimental Study Nermin M. Mohamed1, Rania Hassan Mohamed2, Mahmoud M. Elhefnawi3, Nadia M. Hamdy1 1 Biochemistry Department, Faculty of Pharmacy, Ain Shams University, Abassia 11566, Cairo, Egypt, 2 Biochemistry Department, Faculty of Science, Ain [...]
Sara Abdeljalil Egypt Serum Exosomal LncRNA NAMPT-AS in Breast Cancer: From Molecular Function to Clinical Implications Sara M. Abdeljalil a, Sherehan G. Abdelhamid b, Ramy Ghali c, Montaser B. Yasser d, Mohamed M. Kamal b, e, f, * and Dina H. Kassem b,* a The Environmental Monitoring Center, Central Administration of Environmental Affairs, Ministry [...]
Naledi Pilusa South Africa Fragment screening on S.mansoni glyderaldehyde-3-phosphate dehydrogenase by x-ray crystallography towards the discovery of anti-schistosomal compounds Naledi Pilusa1, Lizbé Koekemoer2, Julia Griese3; Abidemni Paul Kappo1 1Molecular Biophysics and Structural Biology Group, Department of Biochemistry, University of Johannesburg, Johannesburg, South Africa 2Centre for Medicines Discovery, University of Oxford, NDM Research Building, Oxford, Oxfordshire, [...]
Eniola Adesanya Nigeria Fluted Pumpkin Seeds As A Potential Remedy For Trans-Fat Induced Reproductive Damage In Male Wistar Rats Eniola Oluwatomisin Adesanya1, Ayodeji Joseph Ajibare2, Ini-Ibehe Okoko3 1. Department of Human Anatomy, College of Medicine, Lead City University, Ibadan, Oyo State, Nigeria. 2. Neuro-Reproductive and Metabolism Unit, Department of Physiology, Faculty of Basic Medical and [...]
Obaydah Alabrahim Egypt β-Cyclodextrin Nanoparticles Loaded with Boswellia Extract for Enhanced Antimicrobial and Antibiofilm Activity Obaydah Abd Alkader Alabrahim¹, Mostafa Fytory¹,², Ahmed M. Abou-Shanab³, Jude Lababidi¹, Wolfgang Fritzsche⁴, Nagwa El-Badri³*, Hassan Mohamed El-Said Azzazy¹,⁴* 1. Department of Chemistry, School of Sciences & Engineering, The American University in Cairo, AUC Avenue, P.O. Box 74, New [...]
Oleksandr Mushii Ukraine MicroRNA-Based Multiple Logistic Regression Models for Predicting Molecular Subtypes of Breast Cancer R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, 45 Vasylkivska St., 03022, Kyiv, Ukraine Abstract Background Molecular classification of breast cancer (BC) is a key element of personalized treatment, as the molecular subtype [...]
Ahmed Kabel Egypt Fraxetin mitigates doxorubicin-induced cardiotoxicity Ahmed M. Kabel1, Samir A. Salama2, Almokhtar A. Adwas3, Aya A. Kabel4, Remon S. Estfanous5 1. Department of Pharmacology, Faculty of Medicine, Tanta University, Tanta 31527, Egypt 2. Division of Biochemistry, Department of Pharmacology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia 3. [...]